Description
1,10-Phenanthroline is a metal chelator and inhibitor of metalloproteases. 1,10-Phenanthrine acts as a fungistatic against P. verrucosa (MIC = 0.8 μg/ml) and inhibits zinc-induced P. verrucosa metallo-type peptidase activity in a concentration-dependent manner. It reduces the expression of matrix metalloproteinase (MMP3) during chondrogenic differentiation of human chondrocytes.
Datasheet
| SKU-Size | B3122-5G (Size: 5g) B3122-10G(Size: 10g ) |
| Alternate Name | 2-Phenanthroline; 4,5-Diazaphenanthrene; o-Phenanthroline; 5,6-dihydro-1,10-phenanthroline |
| Appearance | Off-white solid |
| CAS # | 66-71-7 |
| Molecular Formula | C₁₂H₈N₂ |
| Molecular Weight | 180.2 |
| Purity | ≥ 98% |
| Solubility | ~18 mg/ml in DMSO or Ethanol |
| SMILES | C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1 |
| InChi | InChI=1S/C12H8N2/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1/h1-8H |
| InChi Key | DGEZNRSVGBDHLK-UHFFFAOYSA-N |
| PubChem CID | 1318 |
| MDL Number | MFCD00011678 |
| Handling | Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure. |
| Storage Conditions | -20ºC |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
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